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In ALD, elevated VLCFA levels lead to increased production of mitochondria-derived ROS, impaired ATP synthesis, diminished calcium uptake capacity, mitochondrial DNA oxidation, and impaired mitochondrial oxidative phosphorylation [47,48]

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So Damien told me about the great success he had had in this in modeling aging in the context of predator and prey

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We do balance testing on most of these patients and find abnormalities, and oftentimes balance therapy is effective in these patients with Ehlers-Danlos syndrome, or hypermobility syndrome