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Common symptoms of psoriasis include: Mild to severe itching, burning, or soreness Red patches of skin covered with thick, silvery scales Dry, cracked skin that might bleed Small scaling spots which are frequently teardrop shaped and most often seen in children Thickened, pitted or ridged nails, which could indicate skin buildup underneath Swollen and stiff joints, in addition to any of the above While not a symptom per say, arthritis is a common consequence of psoriasis

Ferroptosis is characterized by the depletion of intracellular GSH and decreased activity of GPx4, which in turn results in the accumulation of lipid peroxides and Fe(II)-catalyzed oxidation of lipids by the Fenton reaction and increased ROS formation

Freshney RI (2015) Culture of animal cells: a manual of basic technique and specialized applications

[DOI] [PubMed] [Google Scholar] 141.Bratic A., Larsson N.G

Currently, diagnosis is based on clinical symptoms, and the criteria for a diagnosis require the presence of two of these clinical features [5]

Prakriya M, Lewis RS (2015) Store-operated calcium channels