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Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, et al

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Cancer cells can selectively be targeted by hypoxia-triggered mechanism because they are found to possess lower oxygen concentration of ~0.022% as compared to normal cells with oxygen concentration of ~29%

The release of Dox from RS liposomes in the TME through the DDA link fracture triggered by ROS or glutathione is seemingly the prerequisite for the formulations to exert their therapeutic action

Bacterial translocation, which occurs via transcellular transport across the intestinal epithelium, is distinct from intestinal permeability and has been observed in both RA and SpA