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The frequency and duration vary too, making it challenging to nail down the optimal treatment approach

Although cysteinyl leukotrienes have long been implicated in airway inflammation and bronchoconstriction, their precise sources and mechanisms of action have remained incompletely understood

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It is also essential for folate and related one-carbon metabolism, where FAD is required as a cofactor for methylenetetrahydrofolate reductase (MTHFR), a key folate-metabolizing enzyme

As expected in Figure S20, our results showed a modest induction of cell death in normal cells, indicating a favorable safety profile for the targeting drug with minimal impact on healthy cells

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