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The majority of genetic polymorphisms are considered innocuous, whereas several single-nucleotide polymorphisms (SNPs) can exert remarkable biological effects

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4 Brain organoids: screening or drug repurposing in models of mitochondrial diseases One of the more relevant questions for the researchers is whether organoids might replace or reduce the use of animal models in drug screening and cancer immortalized cell lines in high-throughput screening (HTS) (Lampart et al., 2023)

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