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The pathways associated with hypoxia and dysregulated immune system have been identified as strong drivers of neurological complications of post-acute sequelae of SARS-CoV-2 infection (evidence from the post-mortem brain studies and observational studies) [97]

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A sixth patient missed the V1 visit but all other data points were included in the final analysis

Figure 3 shows the prediction-corrected VPC plots, where most observed data fell within the 95% confidence interval (CI) generated by model simulations, showing that the final model had good forecasting ability