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Description

Specifically, Keytruda was approved in combination with chemotherapy to treat adults with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma

Discussion Clinical trials have indicated that leptin administration failed as an efficient therapeutical approach to treat obesity 24,25,26 , although it attenuates the neuroendocrine and metabolic changes induced by weight loss 1,2,3,4,5

The pathway may still be active, but may nonetheless not be necessary for the endpoint being investigated

RNA extraction, RT-PCR, and real-time PCR Total RNA extraction was performed using the Maxime RT Premix Kit (iNtRON Biotechnology) according to the manufacturers instructions