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Sleep disorders is correlated with a variety of diseases and have been implicated as a predictor for Alzheimer, Parkinson, and Huntington's diseases, many of these diseases are also associated with oxidative damage [37,38]

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The role of ubiquitination and proteosomal protein degradation in the regulation of CBS levels is highlighted by studies of the Kruger group who demonstrated that pharmacological inhibition of proteosomal activity can increase cellular CBS protein levels [29]

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3b, gels 3 and 4)

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Several studies have highlighted the role of microparticles in several SCD complications, such as vaso-occlusion and kidney dysfunction [134,135,136]

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Interestingly, ParaBacteroides responses appear to vary between studies, as Buchenauer et al

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Epigenetics in neurological and psychiatric disorders: a comprehensive review of current understanding and future perspectives

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