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CSF collection is a highly invasive technique requiring specialised medical staff and is not practical as an initial assessment

BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states

Dysregulation of this neuroendocrine system is evident in conditions such as COPD and in severe infections, such as COVID-19

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Upon starvation, CLUH inhibits mTORC1 activation and mitochondrial anabolic pathways, promoting mitochondrial turnover and allowing efficient metabolic reprogramming