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doi: 10.1016/j.jaci.2016.09.023

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Estudios en modelos animales sugieren efectos ansiolticos y antidepresivos, posiblemente mediados por la interaccin con los sistemas dopaminrgico y serotoninrgico

In lipid metabolism, overexpression of sphingomyelinase (SMase) may increase ceramide production, which has been implicated in the activation of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) signaling, ultimately contributing to trophoblast apoptosis (25)