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Because the process works in a few different situations

Cells 10, 1824

10.2478/v10136-011-0003-6 30 QiuX.WangP.WangD.WangM.YuanY.ShiZ

Reduced inflammation characterized by a reduction in plasma levels of TNF was also observed in response to CoPP treatment post MI, while HO-1 induction also increased the activity of the Akt pro-survival pathway in cardiomyocytes (122)