chemical composition of tobacco leaves PDF] and Cigarette Smoke in Two Brands of New Zealand Cigarettes Figure 3.1, Tobacco alkaloids -

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The process involves a careful control of heat and humidity: Yellowing the Leaf (20 to 40 hours) -too much heat or too little humidity results in green tobacco -yellowing too long results in useless "dead" leaves Drying the Leaf (2-4 days) -too much heat or too rapid an increase in heat blotches or scalds the leaf brown -too slow an increase in heat or too much humidity also creates "dead" leaf Factors to watch during the curing process include: -moisture in the leaves when they were primed -ripeness of the leaf when it is put in the kiln -weather conditions which can affect temperature and humidity inside the kiln Once the leaves are dried (confirmed by checking the stems, the last part of the leaf to dry) the tobacco is allowed to cool and the doors to the kiln are opened in order to allow the humid night air to case or soften the dry leaves

Their pilot study enrolled nine healthy non-smokers or former smokers without significant chronic medical conditions who were at least 18 years old, had used electronic cigarettes at least 2 months prior to participation, and used electronic cigarettes at least eight times daily

they did the same for tobacco from the cigarette brand they preferred

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The R 2 value obtained suggests that the regression model effectively predicted and explained the relationship between the independent variables and the response