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Peyronie's Disease Causes The cause of Peyronies disease is mostly unknown in the medical field, and extensive research continues to unravel more about this disease

P., and Zhu, L

Together, these interconnected mechanisms, metabolic-energetic regulation (energy demands, redox balance), neuroimmune crosstalk (pro-inflammatory/anti-inflammatory balance), neural excitation-inhibition equilibrium, and PTMs (e.g., methylmalonylation, propionylation and lactylation), in conjunction with glial networks, neurovascular coupling, and ECM remodeling collectively maintain CNS homeostasis