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10.1177/1934578X1000501236 201 PrompetcharaE.KetloyC.PalagaT

Supports antioxidant protection and overall wellness

Furthermore, METTL3 can promote gastric carcinogenesis by activating the METTL3/m6A/miR-1184 axis via an m6A-dependent mechanism, thereby interfering with the miR-1184/TRPM2 signaling pathway (34).Recent findings indicate that the demethylase ALKBH5, which regulates ZKSCAN3 expression via N 6 -methyladenosine (m 6 A) modification, activates VEGFA transcription and facilitates MNNG-induced gastric cancer cell migration, invasion, cancer stem cell (CSC) generation, vasculogenic mimicry (VM), and ultimately, gastric cancer progression (13)

doi: 10.1016/j.ebiom.2016.10.036 425 TiderencelKAHutcheonDAZieglerJ

doi: 10.1007/BF00686114

We used four tumor-normal pairs for training, and evaluated the prediction performance on test sets consisting of the two remaining pairs, constituting a threefold cross-validation