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Therefore, this requires the identification of more specific and suitable downstream targets

A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy

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49 When adjusting for covariates, cause-specific Cox regression was used to model the treatment effect and covariates on time to outcome

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The dual 10mg configuration (20mg total) is exceptionally suitable for extended research timelines and highly controlled experimental designs