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Furthermore, VLDL readily undergoes oxidative modification and serves as a key substrate for lipoprotein-associated phospholipase A2 (Lp-PLA2), generating substantial amounts of lysophosphatidylcholine (LPC) [118]

Xu and colleagues discovered that Ficolin B, carried by exosomes from alveolar macrophages, exacerbates bleomycin-induced lung injury and fibrosis by promoting ferroptosis through the cGAS/STING signaling pathway [113]