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Patients with severe disease (MDF score of 32, with or without hepatic encephalopathy) and lacking contraindications to steroid use should be considered for a four week course of prednisolone (40 mg/day for 28 days, typically followed by discontinuation or a 2-week taper) (Class I, level A)

The medication can be kept at room temperature for short periods during preparation, but prolonged exposure should be avoided

The DEG analysis was performed by means of the GEO2R tool[131, 132] in the GEO website ( DEGs were selected with the fold change (FC) threshold of 1.2 and adjusted P -value threshold of 0.05

Protection restores confidence in execution

It is exceptionally high in cysteine

Kasprzak A