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KD used to treat refractory seizures in children was leading to the appearance of kidney stones 13,26

Data-driven prevention

11 The F.D.A

After remethylation, methionine can be reused to produce SAMe, the bodys universal methyl donor, which participates in several key metabolic pathways, including methylation of DNA and myelin, synthesis of carnitine, coenzyme Q 10 (CoQ 10 ), creatine, epinephrine, melatonin, methylcobalamin, and phosphatidylcholine (PC), as well as phase 2 methylation detoxification reactions