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From a chemical compatibility perspective, adding bacteriostatic water to a third-party peptide can produce unpredictable results if the peptide material has an unsuitable pH, contains residues from manufacture, has degraded during storage, or has poor solubility characteristics

Vitamin B12 is one of eight water-soluble B vitamins that are co factors in almost all biochemical pathways, however sources of it are limited

doi:10.1016/S0140-6736(69)91856-X

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Consequently, even prolonged systemic therapy frequently fails to achieve therapeutic intraocular levels, leading to persistent or recurrent ocular inflammation (Multani et al., 2022)