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A study of 3D organotypic nasal epithelial culture showed that the impact of IQOS was substantially lower than CS in terms of cytotoxicity, tissue morphology, proinflammatory mediators, ciliary function, transcriptome perturbations, and miRNA expression profiles 59

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[35] [36] [37] In 2009, Swedish Match entered an agreement with Philip Morris International and formed the joint venture company SMPM International, with equal stakes owned by each of the two partners, for exploring and developing new markets for snus and other smokefree tobacco products outside Scandinavia and the United States

Tobacconists in Seville and Ballarat were targeted by arson attacks early this year

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ASTHO will continue to track state and federal laws on this important policy topic and share updates as appropriate.